Comparison of Duct Tape with Adhesive Cyanoacrylate versus Cryotherapy in the Treatment of Palmoplantar Warts

Background: Warts are common benign skin growths that appear when a virus infects the top layer of the skin. Common therapies for warts include destruction (electrodesiccation, cryotherapy, salicylic acid, laser, etc.), topical immunotherapy and occlusion.

Objective: To evaluate the efficacy of duct tape occlusion therapy with adhesive cyanoacrylate versus cryotherapy for the treatment of warts.

Design: Randomized trial versus comparative cohort.

Methods: Sixty immunocompetent participants with 1-3 warts measuring 3 to 15 mm were enrolled between September 15, 2014, and February 15, 2016. Thirty participants were treated with duct tape, plus adhesive cyanoacrylate (group A), and 30 participants were treated with cryotherapy (group B).

Results: After two months, warts resolved completely, more in participants treated with duct tape, plus adhesive cyanoacrylate (80%) than in participants treated with cryotherapy (60%).

Conclusion: There was statistically significant difference between duct tape with adhesive cyanoacrylate and cryotherapy for the treatment of palmoplantar warts.